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  • Anti-XIAP Polyclonal Antibody
產(chǎn)品名稱:

Anti-XIAP Polyclonal Antibody

產(chǎn)品品牌: SOLARBIO/索萊寶 價格:
廠商性質(zhì): 生產(chǎn)廠家 產(chǎn)品時間: 2022-08-15
Anti-XIAP Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品概述

品牌SOLARBIO/索萊寶貨號K106527P
規(guī)格50ul/100ul供貨周期現(xiàn)貨
主要用途WB應(yīng)用領(lǐng)域醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè)

Anti-XIAP Polyclonal Antibody

英文名稱Anti-XIAP Polyclonal Antibody
宿主Rabbit
別名API3;BIRC4;hIAP-3;hIAP3;IAP-3;ILP1;MIHA;XLP2
應(yīng)用WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat
蛋白分子量54kDa
Gene ID331
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human XIAP
性狀液體
Public Immunogen RangeA synthetic peptide of human XIAP
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP98170
克隆類型Polyclonal Antibody
背景資料This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
 

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